• Pravej Serichetaphongse D.D.S., M.Sc.
• Wacharaporn Tasachan D.D.S., M.Sc.
• Dusidra Sahawat B.Eng., M.Sc.
• Pasutha Thunyakitpisal D.D.S., Ph.D.

Objective To investigate effect of the local hemostatic agent prototype (Dent-Chula100) on some
physical and mechanical properties of the light cured resin composites

Materials and methods Five commercial resin composites (Estelite^® Σ, Filtek^TM Z250, Filtek^TM Z350,
PremiseTM and Tetric^® N-ceram) were used in this study. Materials were prepared following ISO 4049
(2009). One hundred microliters of local hemostatic agent prototype was applied on the surface of each
resin composite for 2 minutes prior the light activation. After the complete polymerization, samples
were examined for the solubility, water absorption, depth of cure and flexural strength as compared
with the untreated group. The data was expressed as mean ± standard deviation and analyzed by
two-way ANOVA and Turkey HSD multiple comparison. All statistical testing was performed at the
95% level of confidence.
Results The local hemostatic agent prototype did not significantly affect on the solubility and water
absorption of all resin composites (p > 0.05). The local hemostatic agent prototype significantly
increased the depth of cure of Estelite^® Σ and Filtek^TM Z250 and the flexural strength of Filtek^TM Z250
and Tetric^® N-ceram (p < 0.05). After applied the local hemostatic agent prototype, all five resin
composites have passed the ISO 4049 (2009) in solubility, water solubility, depth of cure and flexural
strength.

Conclusion Following ISO 4049 (2009), the local hemostatic agent prototype is compatible with
physical and mechanical properties of Estelite^® Σ, Filtek^TM Z250, Filtek^TM Z350, Premise^TM and Tetric^®
N-ceram such as solubility, water absorption, depth of cures and flexural strength.

(CU Dent J. 2011;34:213-22)