• Wilawan Wiboonchan D.D.S.
• Wacharaporn Tasachan D.D.S., Cert. of fellowship in Pedodontics, Diplomate, Thai Board of Pediatric Dentistry

Objective The purpose of this study was to compare between enamel fluoride uptake after professional
topical fluoride gel application and self applied CPP-ACP paste with professional topical fluoride gel.

Materials and methods Forty children, aged from 10 to 12 were recruited and divided into two groups.
Control group was applied professional topical fluoride gel and experimental group was self applied
CPP-ACP paste after professional topical fluoride gel for 4 weeks. Acid-etched enamel biopsy was
performed on labial surfaces of both right and left sides on permanent upper central incisors. Enamel
sample was collected before applying fluoride gel, 30 minutes and 4 weeks after fluoride gel application.
The enamel biopsy sample was measured to determine fluoride concentration and calcium concentration by
using fluoride electrode and atomic absorption spectrophotometer, respectively. The data was analyzed
by Mann-Whitney U Test and one way repeated measures analysis of variance at significant level 0.05

Results This study found that enamel fluoride uptake after 4 week fluoride gel application between
control group (2145.11 ± 193.18 parts per million) and experimental group (4172.41 ± 273.17 parts per
million) was statistically significant difference (p < 0.05). The difference of enamel fluoride uptake
between before applying fluoride gel and after 4 weeks, there was not statistically significant difference
(p > 0.05) in control group but there was statistically significant difference (p < 0.05) in experimental
group.

Conclusion The findings of this investigation can be concluded that CPP-ACP paste affects on the
enamel fluoride uptake after applying fluoride gel for 4 weeks.

(CU Dent J. 2009;32:113-22)